Volume 6, Number 2 (Volume 6, Number 2 2015)                   jdc 2015, 6(2): 119-129 | Back to browse issues page


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Vaziri L, Ahmad Nasrollahi S, Firooz A. Topical corticosteroids. jdc. 2015; 6 (2) :119-129
URL: http://jdc.tums.ac.ir/article-1-5125-en.html

1- Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran
2- Pharmaceutical, Cosmeceutical and Hygienic Formulation Laboratory, Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran
3- Cosmetic Products Research Center, Food and Drug Organization, Tehran, Iran
Abstract:   (2143 Views)
Topical corticosteroids (TCs) are very useful in the treatment of some skin disorders such as eczema and psoriasis. TCs exhibit potent anti-inflammatory and anti-proliferative effects responsible for their efficacy in the treatment of skin disorders. TCs can be classified into different groups according to their potency that depends on the intrinsic activity of the corticosteroid molecule, the characteristics of the vehicle (cream, ointment, lotion) that directly influence patient’s compliance and may modify penetration through the skin. British National Formulary classified them into four potency groups with Class I grouping the most potent molecules (e.g. clobetasol propionate) and Class IV the least potent (e.g. hydrocortisone). In contrast, the American classification considers seven potency groups, with super potent, potent, upper mid-strength, mid-strength, lower mid-strength, mild and least potent.
Full-Text [PDF 439 kb]   (2666 Downloads)    
Type of Study: Review | Subject: Special
Received: 2015/09/1 | Accepted: 2015/09/1 | Published: 2015/09/1

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