Volume 7, Issue 1 (Volume 7, Number 1 2016)                   jdc 2016, 7(1): 31-37 | Back to browse issues page

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Rahmatpour Rokni G, Bahar A, Sharifian M, Emadi Chashmi S N, Kianezhad A H, Raisian M. Hirsutism in premenopausal women in Northern Iran: Etiology and associated clinical findings. jdc. 2016; 7 (1) :31-37
URL: http://jdc.tums.ac.ir/article-1-5174-en.html
1- Department of Dermatology, School of Medicine, Mazandaran Univeristy of Medical Sciences, Sari, Iran
2- Department of Internal Medicine, School of Medicine, Mazandaran Univeristy of Medical Sciences, Sari, Iran
3- Department Pathology, School of Medicine, Babol Univeristy of Medical Sciences, Babol, Iran
4- Department of Dermatology, School of Medicine, Tehran Univeristy of Medical Sciences, Tehran, Iran , naseremad@yahoo.com
5- School of Medicine, Mazandaran Univeristy of Medical Sciences, Sari, Iran
Abstract:   (3974 Views)

Background and Aim: Hirsutism is defined as the presence of terminal hairs in androgen dependent areas like upper lip, cheeks, chin, breasts, lower area of abdomen and thigh in women. The aim of this study was to determine the etiologic factors and clinical features of hirsutism in premenopausal women.

Methods: In this cross-sectional study, 180 premenopausal women with hirsutism who were admitted at a referral dermatologic clinic in a 1-year period were investigated. After taking full medical history and performing physical examinations, a transabdominal ultrasonography of the ovaries, and laboratory evaluation including early morning total and free serum testosterone, prolactin, dehydroepiandrosterone sulfate, FSH, LH and 17-hydroxyprogestron in all patients were performed.

Results: The most common causes of hirsutism were idiopathic (51.1%), polycystic ovarian syndrome (37.7%), hyperprolactinemia (4.4%), adrenal hyperplasia (3.8%), and drug-induced (2.8%). Hirsutism was mild in 93 (51.6%) patients, moderate in 78 (43.3%) patients and severe in 9  (5%) patients. Family history of hirsutism was present in 100 patients. Clinical conditions associated with hirsutism were: acne (58.3%), obesity (55.5%), menstrual irregularity (38.8%), androgenic alopecia (17.7%) and acanthosis negricans (8.4%).

Conclusion: Idiopathic hirsutism and polycystic ovary syndrome were the most common causes of the hirsutism in premenopausal women. Obesity also had a significant role in hirsutism occurrence.

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Type of Study: Research | Subject: Special
Received: 2016/06/20 | Accepted: 2016/06/20 | Published: 2016/06/20

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