Volume 1, Issue 4 (12-2010)                   jdc 2010, 1(4): 201-206 | Back to browse issues page

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Zargari O, Kianifar K. Clinical applications of N-acetylcysteine in dermatology. jdc. 2010; 1 (4) :201-206
URL: http://jdc.tums.ac.ir/article-1-48-en.html
Abstract:   (10051 Views)

N-acetylcysteine (NAC) is the acetylated metabolite of cysteine and is approved by the Food and Drug Administration (FDA) for treating acetaminophen toxicity. By boosting glutathione, NAC acts as an antioxidant and through replenishing glutathione, it can also prevent paracetamol toxicity. From the other hand, NAC has mucolytic and antiinflammatory effects and also is a glutamate precursor and therefore can be used in a variety of diseases. Regarding the various pharmacological effects of NAC and its low rate of adverse events, NAC has attracted increasing interest for a range of indications during the recent years. Here, the possible applications of this drug in dermatology are reviewed.

Full-Text [PDF 336 kb]   (5075 Downloads)    
Type of Study: Research | Subject: General
Received: 2010/11/16 | Accepted: 2010/11/30 | Published: 2013/07/16

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