Dermatology and Cosmetic
پوست و زیبایی
jdc
Medical Sciences
http://jdc.tums.ac.ir
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2008-7470
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jalali
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2023
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شیوع آپنه انسدادی خواب در بیماران پسوریازیس مراجعهکننده به درمانگاه پوست بیمارستان رازی: یک مطالعه مقطعی
The prevalence of obstructive sleep apnea in patients with psoriasis referring to the dermatology clinic of Razi Hospital: a cross-sectional study
عمومى
General
پژوهشي
Research
<span style="font-size:10pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span bold="" class="AbstractBoldChar" new="" roman="" style="font-family:" times=""><span style="font-weight:bold"><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">زمینه و هدف:</span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> هدف مطالعه حاضر، ارزیابی شیوع آپنه اختصاصی خواب در بیماران مبتلا به پسوریازیس مراجعهکننده به بیمارستان رازی است.</span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="page-break-after:auto"><span style="line-height:6pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="font-size:13.0pt"><span style="font-family:"B Nazanin""></span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="page-break-after:auto"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span bold="" class="AbstractBoldChar" new="" roman="" style="font-family:" times=""><span style="font-weight:bold"><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">روش اجرا: </span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">بیماران مبتلا به پسوریازیس در سالهای ۱۳۹۷ و ۱۳۹۸ در این مطالعه مقطعی وارد شدند. بیماران ازنظر دموگرافیک، شاخص شدت ناحیه پسوریازیس (</span></span>PASI<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">)، مدت بیماری، محل سکونت، تحصیلات و همچنین پرسشنامه </span></span>Stop-Bang<span style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> و پرسشنامه </span></span>Berlin<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> جهت ریسک خطر آپنه انسدادی خواب، موردبررسی قرار گرفتند.</span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="page-break-after:auto"><span style="line-height:6pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="font-size:13.0pt"><span style="font-family:"B Nazanin""></span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="page-break-after:auto"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span bold="" class="AbstractBoldChar" new="" roman="" style="font-family:" times=""><span style="font-weight:bold"><span lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">یافتهها:</span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> براساس معیار </span></span>Stop-Bang<span style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> ۴۳ نفر (3/41%) ریسک متوسط و ۲۳ نفر (1/22%) ریسک بالای ابتلا به آپنه انسدادی خواب را داشتند. براساس پرسشنامه </span></span>Berlin<span style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> ۴۸ نفر (2/46%) ریسک بالای ابتلا به آپنه انسدادی خواب را داشتند. میانگین سنی افراد (میانگین = 3/58، انحراف م0عیار = 6/10) در ریسک بالای آپنه انسدادی براساس معیار </span></span>Stop-Bang<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> بهطور معنیداری از میانگین سنی افراد با ریسک متوسط (میانگین = 1/48، انحراف معیار = 1/16، 0039<sub>/</sub>0=</span></span><span class="AbstractItalicChar" style="font-family:SimSun"><span style="font-style:italic"><span dir="LTR" new="" roman="" style="font-family:" times="">P</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">) و ریسک پایین (میانگین = 7/41، انحراف معیار = 8/17، 001<sub>/</sub>0</span></span><span class="AbstractItalicChar" style="font-family:SimSun"><span style="font-style:italic"><span dir="LTR" new="" roman="" style="font-family:" times="">P</span></span></span><<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">) بیشتر بود. همچنین </span></span>BMI<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> بین سه گروه براساس معیار </span></span>Stop-Bang<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> بهطور معنیداری متفاوت بود و در افراد با ریسک بالاتر آپنه انسدادی خواب، </span></span>BMI<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> بالاتر بود (05<sub>/</sub>0</span></span><span class="AbstractItalicChar" style="font-family:SimSun"><span style="font-style:italic"><span dir="LTR" new="" roman="" style="font-family:" times="">P</span></span></span><<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">). در افراد با ریسک بالای آپنه انسدادی خواب براساس معیار </span></span>Berlin<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:"> بهطور معنیداری از افراد با ریسک پایین آپنه انسدادی خواب، بالاتر بود (میانگین 1/31 در مقابل میانگین ۲۶ (001<sub>/</sub>0</span></span><span class="AbstractItalicChar" style="font-family:SimSun"><span style="font-style:italic"><span dir="LTR" new="" roman="" style="font-family:" times="">P</span></span></span><<span lang="AR-SA" style="font-size:12.0pt"><span b="" mitra="" style="font-family:">).</span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="page-break-after:auto"><span style="line-height:6pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="font-size:13.0pt"><span style="font-family:"B Nazanin""></span></span></span></span></span></span></span></span><br>
<span bold="" class="AbstractBoldChar" new="" roman="" style="font-family:" times=""><span style="font-weight:bold"><span dir="RTL" lang="AR-SA" style="font-size:11.0pt"><span b="" mitra="" style="font-family:">نتیجهگیری:</span></span></span></span><span dir="RTL" lang="AR-SA" style="font-size:13.0pt"><span b="" nazanin="" style="font-family:"> یافتههای مطالعه حاضر، آپنه انسدادی خواب را بهعنوان یکی از ناخوشیهای همراه پسوریازیس مطرح میکند.</span></span>
<p><span style="font-size:11pt"><span style="line-height:110%"><span new="" roman="" style="font-family:" times=""><span bold="" class="NormalLeftBoldChar" new="" roman="" style="font-family:" times=""><span style="font-weight:bold">Background and Aim:</span></span> The present study aims to assess the prevalence of obstructive sleep apnea in patients with psoriasis referring to Razi Hospital.</span></span></span><br>
</p>
<p><span style="font-size:11pt"><span style="line-height:110%"><span new="" roman="" style="font-family:" times=""><span bold="" class="NormalLeftBoldChar" new="" roman="" style="font-family:" times=""><span style="font-weight:bold">Methods:</span></span> Participants were assessed for demographic characteristics, Psoriasis Area and Severity Index (PASI), disease duration, place of residence, education level, and were also evaluated using the Stop-Bang and Berlin questionnaires to assess the risk of obstructive sleep apnea. The high and low-risk groups for obstructive sleep apnea were compared regarding these parameters.</span></span></span><br>
</p>
<p><span style="font-size:11pt"><span style="line-height:110%"><span new="" roman="" style="font-family:" times=""><span bold="" class="NormalLeftBoldChar" new="" roman="" style="font-family:" times=""><span style="font-weight:bold">Results:</span></span> Based on the Stop-Bang criteria, 43 individuals (41.3%) had moderate risk, and 23 individuals (22.1%) had high risk of obstructive sleep apnea. According to the Berlin questionnaire, 48 individuals (46.2%) were at high risk for obstructive sleep apnea. The mean age of individuals with high risk of obstructive sleep apnea according to the STOP-BANG criteria was significantly higher than those with moderate risk (mean=58.3, standard deviation=10.6, compared to mean=48.1, standard deviation=16.1, <span b="" class="NormalLeftItalicChar" nazanin="" style="font-family:"><span style="font-style:italic"><span new="" roman="" style="font-family:" times="">P</span></span></span> = 0.039) and low risk (mean=41.7, standard deviation=17.8, <span b="" class="NormalLeftItalicChar" nazanin="" style="font-family:"><span style="font-style:italic"><span new="" roman="" style="font-family:" times="">P</span></span></span>< 0.001). Additionally, BMI differed significantly among the three groups based on the Stop-BANG criteria, with higher BMI observed in individuals at higher risk for obstructive sleep apnea (<span b="" class="NormalLeftItalicChar" nazanin="" style="font-family:"><span style="font-style:italic"><span new="" roman="" style="font-family:" times="">P</span></span></span><0.05). BMI was significantly higher in individuals with high risk of obstructive sleep apnea according to the Berlin criteria compared to those with low risk (mean 31.1 versus mean 26, <span b="" class="NormalLeftItalicChar" nazanin="" style="font-family:"><span style="font-style:italic"><span new="" roman="" style="font-family:" times="">P</span></span></span><0.001).</span></span></span><br>
</p>
<p><span bold="" class="NormalLeftBoldChar" new="" roman="" style="font-family:" times=""><span style="font-weight:bold"><span style="font-size:11.0pt">Conclusion:</span></span></span><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""> The findings of this study highlight obstructive sleep apnea as a comorbidity associated with psoriasis.</span></span></p>
پسوریازیس, آپنه انسدادی خواب, شیوع
psoriasis, obstructive sleep apnea, prevalence
137
143
http://jdc.tums.ac.ir/browse.php?a_code=A-10-1-339&slc_lang=fa&sid=1
Seyedhossein
Jahanbakhsh
سیدحسین
جهانبخش