Volume 9, Issue 2 (2018, Volume 9, Number 2 2018)                   jdc 2018, 9(2): 93-99 | Back to browse issues page

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Oryan M, Hakimi Meybodi M H, Ebrahimzadeh Ardekani M, Kiani B. Efficacy of Pistacia atlantica extract in the treatment of acne. jdc. 2018; 9 (2) :93-99
URL: http://jdc.tums.ac.ir/article-1-5318-en.html
1- Faculty of Natural Resources and Eremology, Department of Forestry, Yazd University, Yazd, Iran
2- Department of Dermatology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , mohammad110eb@yahoo.com
3- Department of Dermatology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract:   (102 Views)
Background and Aim: The use of medicinal herbs for the treatment of skin disease, such as acne, has a long history. The extract of Pistaca atlantica is used to treat various diseases. This study was designed to evaluate the short-term efficacy and safety of Pistaca atlantica extract for the treatment of mild to moderate acne.
Methods: This clinical trial was performed on 60 patients with mild to moderate acne, who where randomly divided into two groups. After obtaining informed consent, volunteers in the case group received a topical extract of 15% Pistaca Atlantica once daily for 6 weeks. In the control group, placebo was given in the same way. Patients were evaluated for the number of lesions at the beginning, and 3 and 6 weeks after treatment.
Results: At the end of study, the mean reduction in lesions was 59.93% in the Pistaca atlantica group and -11.46% in the control group. Also Skin softness and lucidity were observed in the Pistaca atlantica group.
Conclusion: This clinical study showed that topical treatment with Pistaca atlantica extract can be recommended to improve mild to moderate acne. However, a longer study with larger sample size is needed to achieve a comprehensive evaluation of the efficacy and safety of this plant.
Full-Text [PDF 212 kb]   (47 Downloads)    
Type of Study: Research | Subject: Special
Received: 2018/09/11 | Accepted: 2018/09/11 | Published: 2018/09/11

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