Journal of

Background and Aim: The aim of this study was to evaluate surgery approach outcomes in patients with squamous cell carcinoma (SCC) of lower lip.

Methods: We retrospectively analyzed medical records of patients that diagnosed with SCC of the lower lip at Razi hospital at Tehran University of Medical Sciences in a 5 year period. Data analysis included descriptive statistics and bivariate analyses using the chi-square and Fisher’s exact tests to compare the variables.

Results: The age range of patients was 35 to 94 years (mean, 64.1 years; SD, 13.27 years), with a 5:1 male-female ratio. SCC of the lower lip occurred more frequently in patients older than 60 years. 62.1 % of the patients were addicted to cigarette and other tobacco compounds. It was noted
sig­nificant association between chronic solar exposure in the job’s environment and incidence of SCC in lower lip. Mean diameter of the tumor was 28.1 mm (range, 5 to 63 mm). Recurrence was detected in 17 patients (24.6%). Two patients (2.89%) died due to lower lip SCC in this series.

Conclusion: our study revealed that lower lip SCC is more prevalent in men and in eighth decade of life. As well, considering the low recurrence rate and high survival rate, surgery could be considered as an effective method of treatment.