Volume 16, Issue 4 (Volume 16, No 4 2026)
Dermatol Cosmet. 2026, 16(4): 247-267 |
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Khayyat Sarkar Z, Akbari Adergani B, Nasri F, Aleboyeh M. Advantages, challenges, and safety considerations of nanotechnology applications in the cosmetic industry: a narrative review. Dermatol Cosmet. 2026; 16 (4) :247-267
URL: http://jdc.tums.ac.ir/article-1-5827-en.html
URL: http://jdc.tums.ac.ir/article-1-5827-en.html
1- Food and Drug Research Center, Food and Drug Administration, Ministry of Health and Medical Education, Tehran, Iran
2- Water Safety Research Center, Food and Drug Administration, Ministry of Health and Medical Education, Tehran, Iran ,b.akbari@fda.gov.ir
2- Water Safety Research Center, Food and Drug Administration, Ministry of Health and Medical Education, Tehran, Iran ,
Abstract: (15 Views)
Over the past two decades, nanotechnology has played a pivotal role in transforming the cosmetic and personal care industry, establishing itself as one of the most revolutionary achievements in materials science. The reduction of particle size to the nanometer scale, by increasing the specific surface area and enhancing physicochemical properties, has enabled improved skin penetration, increased stability of active compounds, and facilitated the targeted release of active ingredients, leading to the production of products with higher efficacy. However, concurrent with the expansion of this technology, concerns regarding the biosafety, potential toxicity, and environmental consequences of nanoparticles have been raised, highlighting the necessity for rigorous evaluation. Therefore, this article aims to provide a comprehensive analysis of the advantages, limitations, and safety considerations associated with the application of nanotechnology in the cosmetic and personal care industry. In this analytical review, articles and sources published in reputable scientific databases between 2015 and 2025 were evaluated and analyzed. The results indicated that the utilization of nanostructures such as nanoliposomes, nanoemulsions, metallic nanoparticles, and lipid nanoparticles in the formulation of cosmetic products, while optimizing performance and increasing bioavailability, has created significant potential for innovation in this industry. Conversely, evidence has been reported regarding the induction of oxidative stress, inflammatory responses, and regulatory challenges in the context of long-term risk assessment. The application of nanotechnology in the cosmetic and personal care industry holds substantial innovative capacity and high added value; nevertheless, ensuring consumer safety necessitates long-term toxicological studies and the development of clear regulatory frameworks. Establishing a balance between industrial innovation and public health considerations is a fundamental condition for the sustainable development of this technology.
Keywords: nanotechnology, nanoparticles, cosmetic and personal care industry, toxicity, regulatory framework
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